INVERSE LANGMUIR METHOD FOR OLIGONUCLEOTIDE MICROARRAY ANALYSIS

Inverse Langmuir method for oligonucleotide microarray analysis

Abstract Background An algorithm for the analysis of Affymetrix Genechips is presented.This algorithm, referred to as the Inverse Langmuir Method (ILM), estimates the binding of transcripts to complementary probes using DNA/RNA hybridization free energies, and the hybridization between partially complementary transcripts in solution using RNA/RNA f

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Chlamydia trachomatis serotype A infections in the Amazon region of Brazil: prevalence, entry and dissemination

INTRODUCTION: Chlamydia infection is associated with debilitating human diseases including trachoma, pneumonia, coronary heart disease and urogenital diseases.Serotypes of C.trachomatis show a fair correlation with the group of diseases they cause, and their distribution follows a well-described geographic pattern.Serotype A, a trachoma-associated

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Long-term follow-up of surgical resection alone for primary intracranial rostrotentorial tumors in dogs: 29 cases (2002-2013)

Intracranial neoplasia is frequently encountered in dogs.After a presumptive diagnosis of intracranial neoplasia is established based on history, clinical signs and advanced imaging characteristics, the decision to treat and which treatment to choose must be considered.The objective of this study is to report survival times (ST) for dogs with intra

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